From equity to priority setting: Where we can improve funding epidemic and pandemic research for the future

Nearly two years into the COVID-19 pandemic, the global research community has begun to take stock of lessons learned when it comes to funding research during a global health crisis, especially in LMICs.

Aimed at global research funders, the new report from UKCDR and GloPID-R’s COVID Research Coordination & Learning (COVID CIRCLE) initiative draws on its comprehensive database of more than 13,000 funded COVID-19 research projects across 160 countries held in the COVID-19 Research Project Tracker.

The report identified a number of barriers experienced by funders and researchers across the globe in the process of undertaking and funding COVID-19 research. These barriers include issues of equity and access, and delays to, and sometimes a lack of, regionally developed research priorities, hindering the alignment of funding and research.

Key lessons for funders from this pandemic that will enable future funding preparedness and response include:

• the appreciation of the early development of the WHO & GloPID-R Research Roadmap;
• leveraging pre-existing partnerships and funding to enable rapid response;
• the need for greater support for open science and data sharing practices in epidemics, along with buy-in and support of LMICs;
• the need for greater global funder collaboration.

Many examples of best research practice and innovative funding mechanisms that have taken place during the pandemic to date are highlighted. Examples of these are the European and Developing Countries, Clinical Trial Partnership (EDCTP) rapid emergency funding mechanism which mobilised €12.75m for research implemented in 25 Sub-Saharan African countries.

The report also provides specific recommendations on the actions that funders could pursue to improve the implementation of the Funder Principles, particularly in low-resource settings.

These include the need for greater long-term funding of networks which would provide the capacity to pivot to emerging diseases; the need for greater guidance, support and systems to realise Open Science; and greater global coordination including joint funding mechanisms.

Lessons learned in the report are framed around COVID CIRCLE’s ‘Funder principles for research in epidemics Funders Principles for Supporting High-Quality Research for the Most Pressing Global Needs in Epidemics and Pandemics’ which build on best practice guidance from key stakeholders and include commitments to ensure that research outputs are shared rapidly to inform policy and practice in epidemic situations. These have been embedded into funding practices e.g. the Global Effort on COVID-19 Health Research (GECO) included adherence to the principles in its funding call guidelines.

The challenges and potential solutions for achieving the Funder Principles require action from a range of stakeholders. The authors of the report issue an urgent call for the Principles to be endorsed by research funders: they call upon donors, governments and any other entities supporting research to address needs during the current as well as future epidemics and pandemics.

Sir Jeremy Farrar, Director, Wellcome Trust said:

“We shouldn’t be stopping our efforts now. Covid-19 still threatens society, particularly in low-resource settings. Funding research only in high-income countries won’t halt its progress. It remains crucial to continue collaborative research with low- and middle-income countries to ensure we don’t repeat mistakes in response to future pandemics.”

Prof. Charles Wiysonge, GloPID-R Vice Chair, South Africa said:

“GloPID-R is excited to move this agenda forward through its LMIC funder working group and through an ongoing drive to expand regional membership and improve collaboration and cohesion of research funding preparedness and response.” 

Dr Alice Norton, Research Lead for COVID CIRCLE and corresponding author said:

“The COVID CIRCLE principles set a benchmark for research funding and coordination for the most pressing global needs in an epidemic or pandemic. We would like to encourage more funders to embed them into their practices. Through creating mechanisms for greater funding efficiency, we can channel funding into the spaces with the greatest need that are currently under-researched.” 

Virtual dialogue

To launch the report, a virtual event is being held this afternoon (2^nd November, 14:00-15:30 GMT), co-hosted by UKCDR and GloPID-R. The dialogue will hear directly from the funders on their reflections from funding COVID-19 research and the best practices to retain for future epidemic and pandemic situations, with a specific focus on low-and middle-income countries. Still a chance to sign up here

Links

• Read the report: Funding and undertaking research during the first year of the COVID-19 pandemic – COVID CIRCLE lessons
• Read the case studies: A collection of research projects and programmes demonstrating innovative best practice in research in epidemics

NOTE TO EDITORS

Media contacts

UKCDR

Nicole Huxley (UK)

n.huxley@old-ukcdr.s14staging.uk

+44 (0)20 7611 2093

GloPID-R

Mary Shaffer (France)

mary.shaffer@ext.fondation-merieux.org